A dual-modality probe utilizing intravascular ultrasound and optical coherence tomography for intravascular imaging applications.

Publication Type:

Journal Article

Source:

IEEE transactions on ultrasonics, ferroelectrics, and frequency control, Volume 57, Issue 12, p.2839-43 (2010)

Keywords:

Animals, Aorta, Equipment Design, Image Processing, Computer-Assisted, Phantoms, Imaging, Rabbits, Signal Processing, Computer-Assisted, Tomography, Optical Coherence, Transducers, Ultrasonography, Interventional

Abstract:

We have developed a dual-modality biomedical imaging probe utilizing intravascular ultrasound (IVUS) and optical coherence tomography (OCT). It consists of an OCT probe, a miniature ultrasonic transducer and a fixed mirror. The mirror was mounted at the head of the hybrid probe 45° relative to the light and the ultrasound beams to change their propagation directions. The probe was designed to be able to cover a larger area in blood vessel by IVUS and then visualize a specific point at a much finer image resolution using OCT. To demonstrate both its feasibility and potential clinical applications, we used this ultrasound-guide OCT probe to image a rabbit aorta in vitro. The results offer convincing evidence that the complementary natures of these two modalities may yield beneficial results that could not have otherwise been obtained.

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PMCID 
PMC3059782